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Brand names Why is this medication prescribed? Tadalafil Cialis is used to treat erectile dysfunction ED, impotence; inability to get or keep an erection , and the symptoms of benign prostatic hyperplasia BPH; an enlarged prostate which include difficulty urinating hesitation, dribbling, weak stream, and incomplete bladder emptying , painful urination, and urinary frequency and urgency in adult men.

Tadalafil Adcirca is used to improve the ability to exercise in people with pulmonary arterial hypertension PAH; high blood pressure in the vessels carrying blood to the lungs, causing shortness of breath, dizziness, and tiredness.

Tadalafil is in a class of medications called phosphodiesterase PDE inhibitors. It works to treat erectile dysfunction by increasing blood flow to the penis during sexual stimulation.

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Tadalafil was found to have similar benefits for lower urinary tract symptoms as the usually prescribed tamsulosin. Mechanism of action[ edit ] Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and the smooth muscle of the corpus cavernosum. However, because sexual stimulation is required to initiate the local penile release of nitric oxide, tadalafil’s inhibition of PDE5 will have no effect without sexual stimulation.

Furthermore, the longer half-life is the basis for tadalafil’s daily therapeutic use in treating pulmonary arterial hypertension.

Comparison with actions of other PDE5 inhibitors[ edit ] Sildenafil and vardenafil inhibit PDE6, an enzyme found in the eye, more than tadalafil. Tadalafil can be synthesized starting from D – tryptophan methyl ester and piperonal via a Pictet—Spengler reaction.

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Back to Tadalafil About tadalafil – Brand names: Cialis, Adcirca Tadalafil is a medicine used to treat erection problems erectile dysfunction and symptoms of an enlarged prostate benign prostate enlargement.

It’s also sometimes used to treat pulmonary hypertension high blood pressure in the blood vessels that supply the lungs. If you have erection problems, tadalafil works by temporarily increasing blood flow to the penis when you get sexually excited. If you have symptoms of an enlarged prostate gland, such as difficulty peeing or needing to pee urgently, tadalafil works by relaxing the muscles in the prostate and bladder.

In pulmonary hypertension it works by relaxing blood vessels in the chest. Tadalafil is available on prescription only.

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A small number of patients taking Cialis also reported abnormal vision. What important information should you know about Cialis? CIALIS can cause your blood pressure to drop suddenly to an unsafe level if it is taken with any nitrate medication.

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If you have an erection that lasts for more than 4 hours, you should go to the nearest hospital emergency department. Prolonged erections can be dangerous. Tadalafil may not be safe for people with certain medical conditions, including people who have had a stroke , have coronary heart disease or retinitis pigmentosa an eye disease.

It can also interact with many medicines, particularly nitrates used in some types of heart disease and blood pressure medicines. If you take nitrates in any form, or are on treatment for pulmonary hypertension , you should not take tadalafil.

If you are thinking about using tadalafil please discuss it with your doctor. How can I buy tadalafil? You need a prescription from a doctor to buy tadalafil.

You can buy it from a store-based pharmacy or reputable online pharmacy with a prescription.

You can use Cialis on a daily basis at a lower dosage. Cialis Daily helps to prevent erectile dysfunction 24 hours a day. This may be a good option if you plan to have sex at least times a week. Cialis Daily will come in doses of 2. This type is best if you do not plan to have sex regularly, but want to have the medication on hand.

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