Do not keep out-of-date or unwanted medicines. After 24 weeks of dapoxetine therapy, the trial by Buvat et al found Importantly, clear evidence was found for improvements in interpersonal relationships, suggesting that both sexual partners benefitted from dapoxetine treatment. Do not stop taking tadalafil without talking to your doctor. Interpersonal difficulty related to ejaculation Changes from baseline in interpersonal difficulty related to ejaculation following dapoxetine therapy were reported in five studies Table 3. The table below contains some of the most common ones associated with dapoxetine.lasts up to 36 hours for some people, which is longer than Viagra. can be taken as needed or on a daily, regular basis. daily use allows for a more spontaneous sex life. can be taken with or. The metabolites of dapoxetine are eliminated rapidly in the urine with a terminal half-life of and hours for a single dose of 30 mg and 60 mg, respectively. Safety and tolerability Cardiovascular safety. The cardiovascular safety profile of dapoxetine has been studied extensively during the drug development. Phase I trials showed that. Cialis (tadalafil) increase increases blood flow to a certain area of the body and is used to treat erectile dysfunction (impotence). Includes Cialis side effects, interactions and indications.