Is tadalafil safe? It may be difficult to remain firm despite wanting to have sex. Taking generic ED medications is an effective way to save money without sacrificing quality. Both options require valid medical documentation, but some online services only require a health questionnaire to be filled out and reviewed for approval—meaning no face-to-face video interaction is needed. What is in tadalafil? Tadalafil is generally safe for most men with ED.Cialis (tadalafil) is a prescription medication for those with erectile dysfunction. Many providers sell Cialis online — learn about the safest and most discreet providers here. If you’re interested in getting a day supply of tadalafil, talk with your doctor or insurance provider. Use a mail-order pharmacy to get your medication. Tadalafil is a generic drug that comes in the brand-name versions Cialis, Adcirca, and Alyq.A generic drug is an exact copy of the active drug in a brand-name medication.