Hence, seeking medical assistance before taking this medicine is very important. Taking this medicine with any other drugs which have the content of Tadalafil can be riskier. Never use it with nitrates as it can drastically lower your blood pressure levels and Riociguat can also have some serious effects as it reacts with this medicine. You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail. If you ever need emergency medical treatment for a heart problem, the health care providers who treat you will need to know when you last took tadalafil. Sexual activity may be a strain on your heart, especially if you have heart disease.There are many ways to save on Cialis, which is available as both a brand-name and generic medication. Save with GoodRx. GoodRx can help you save over 97% off the . Cialis comes as a tablet you swallow. It contains the active ingredient tadalafil. (An active ingredient is what makes a drug work.) Keep reading for details on Cialis and cost, and . Follow Us; Health Conditions; Health Products 20 mg; However, doctors usually suggest starting with the 10 mg pills. The price for tadalafil is $ per month, while Cialis is $